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The following further unwanted side effects have been observed with Simponi: Very common unwanted side effects (could have an effect on more than 1 in 10 folks): Upper respiratory tract infections, sore throat or hoarseness, runny nose Common unwanted effects (may affect as much as 1 in 10 individuals): Abnormal liver tests (increased liver enzymes) discovered throughout blood checks accomplished by your doctor Feeling dizzy Headache Feeling numb or having a tingling feeling Superficial fungal infections Abscess Bacterial infections (such as cellulitis) Low pink blood cell counts Low white blood cell counts Positive blood lupus check Allergic reactions Indigestion Stomach pain Feeling sick (nausea) Flu Bronchitis Sinus infection Cold sores High blood stress Fever Asthma, shortness of breath, wheezing Stomach and bowel disorders which embrace inflammation of the abdomen lining and colon which may trigger fever Pain and ulcers within the mouth Injection web site reactions (together with redness, hardness, ache, bruising, itching, tingling and irritation) Hair loss Rash and itching of the pores and skin Difficulty sleeping Depression Feeling weak Bone fractures Chest discomfort Uncommon unwanted side effects (may have an effect on up to 1 in one hundred individuals): Kidney infection Cancers, together with pores and skin most cancers and non-cancerous growths or lumps, together with skin moles Skin blisters Severe an infection throughout the body (sepsis), generally together with low blood stress (septic shock) 204 Psoriasis (including on the palms of your hand and/or the soles of your feet and/or in the type of skin blisters) Low platelet count Combined low platelet, pink, and white blood cell count Thyroid disorders Increase in blood sugar levels Increase in blood cholesterol levels Balance issues Vision disturbances Inflamed eye (conjunctivitis) Eye allergy Sensation of heart beating irregularly Narrowing of the blood vessels within the heart Blood clots Flushing Constipation Chronic inflammatory situation of the lungs Acid reflux Gall stones Liver problems Breast issues Menstrual disorders Rare side effects (might have an effect on as much as 1 in 1,000 individuals): Failure of the bone marrow to supply blood cells Severely decreased number of white blood cells Infection of the joints or the tissue round them Impaired healing Inflammation of blood vessels in inner organs Leukaemia Melanoma (a type of skin most cancers) Merkel cell carcinoma (a sort of pores and skin most cancers) Lichenoid reactions (itchy reddish-purple pores and skin rash and/or threadlike white-grey strains on mucous membranes) Scaly, peeling skin Immune problems that could have an effect on the lungs, skin and lymph nodes (mostly presenting as sarcoidosis) Pain and discolouration within the fingers or toes Taste disturbances Bladder issues Kidney issues Inflammation of the blood vessels in your pores and skin which leads to rash Side effects of which the frequency is not identified: A rare blood most cancers affecting largely young people (hepatosplenic T-cell lymphoma) Worsening of a condition known as dermatomyositis (seen as a skin rash accompanying muscle weakness) Reporting of unwanted effects If you get any unwanted side effects, speak to your physician, pharmacist or nurse. 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