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4, 113 For patients treated with bortezomib based therapy, the lack of a hematologic response after 2 cycles is usually a signal to change therapy and, in most cases, bortezomib and dexamethasone will be retained but other agents such as melphalan or immune modulatory drugs are added best site to buy priligy canada 30 32 High suPAR levels predispose patients to AKI in various clinical scenarios including critical illness, likely by modulating mitochondrial respiration and inducing reactive oxygen species generation in proximal tubular cells, sensitizing them to additional damage

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