Mutation prevalence varies amongst racial and ethnic groups, with associated illness severity. It is the responsibility of the medical practitioner signing the death certificate to indicate which morbid conditions led directly to death and to state any antecedent conditions giving rise to this cause. Epidermal nerve fibers are affected early in the course of most peripheral neuropathies compared to giant myelinated nerve fibers medications given to newborns generic 0.2% alphagan mastercard.